Speaker

Charles completed his MBPhD training in 1999 at the Imperial Cancer Research Fund Laboratories and Cancer Research UK clinician scientist/medical oncology training in 2008. He is a senior Principal Investigator and of the Cancer Evolution and Genome Instability Laboratory, and Deputy clinical director at the Francis Crick Institute. He combines his research with clinical duties at UCLH as a Consultant thoracic oncologist, focussed on how tumours evolve over space and time. His research branched evolutionary histories of solid tumours, processes that drive cancer cell-to-cell variation in the form of new cancer mutations or chromosomal instabilities, and the impact of such cancer diversity on effective immune surveillance and clinical outcome. Charles is chief investigator of TRACERx, a lung cancer evolutionary study, the national PEACE autopsy program, and the TRACERx EVO study.